Condition | Recommended antihypertensive drugs |
---|
No target organ damage |
Uncomplicated hypertension | Ace inhibitor, ARB, calcium-channel blocker, diuretic |
Target organ damage or cardiovascular disease |
LVH | ACE inhibitor, ARB, calcium-channel blocker, diuretic |
Microalbuminuria or proteinuria | ACE inhibitor, ARB |
Renal damage without albuminuria http://www.dynamed.com/management/hypertension-medication-selection-and-management#CHRONIC_KIDNEY_DISEASE | ACE inhibitor, ARB; calcium-channel blocker, diuretic (furosemide if eGFR < 30 ml/min/1.73 m2 ) |
History of stroke | ACE inhibitor, ARB, calcium-channel blocker, diuretic |
History of MI http://www.dynamed.com/management/hypertension-medication-selection-and-management#EVIDENCE__CORONARY_ARTERY_DISEASE_ | Beta-blocker (for the first year), ACE inhibitor (ARB if ACE inhibitor unsuitable) |
Symptomatic coronary artery disease http://www.dynamed.com/management/hypertension-medication-selection-and-management#EVIDENCE__CORONARY_ARTERY_DISEASE_ | Beta-blocker, calcium-channel blocker |
Heart failure http://www.dynamed.com/management/hypertension-medication-selection-and-management#EVIDENCE__HEART_FAILURE_ | ACE inhibitor, ARB, diuretic, beta-blocker, aldosterone antagonist |
Atrial fibrillation |
| ARB, ACE inhibitor, beta-blocker |
| Beta-blocker, verapamil (note, these two agents should not be combined) |
Peripheral artery disease | ACE inhibitor, ARB, calcium-channel blocker |
Special situations |
Diabetes http://www.dynamed.com/management/hypertension-medication-selection-and-management#DIABETES | ACE inhibitor, ARB, calcium-channel blocker, diuretic |
Gestational hypertension | Beta-blocker, combination of alpha and beta blocker (labetalol), calcium-channel blocker with dihydropyridine structure (nifedipine) |
Asthma | Calcium-channel blocker, ARB, diuretic |