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Evidence summaries

Prognostic Role of Troponin T Versus Troponin I in Unstable Angina Pectoris

Troponin T and troponin I predict adverse cardiac events in patients with unstable angina pectoris. Level of evidence: "A"

A systematic review 1 including 12 studies on troponin T (n=2,847) and 9 studies on troponin I (n=1,901) was abstracted in DARE. For troponin T the cumulative OR for the risk of acute myocardial infarction was 2.7 (95% CI 2.1 to 3.4. The cumulative sensitivity attributable to troponin T for adverse cardiac events was 57% with a cumulative specificity of 68%. For troponin I, the corresponding OR was 4.2 (95% CI 2.7 to 6.4), and the cumulative sensitivity and specificity were 63% and 71%, respectively. In comparative analysis of troponin T vs troponin I, the SROC showed no statistically significant difference between the sensitivity and specificity of troponin T and I.

References

  • Olatidoye AG, Wu AH, Feng YJ, Waters D. Prognostic role of troponin T versus troponin I in unstable angina pectoris for cardiac events with meta-analysis comparing published studies. Am J Cardiol 1998 Jun 15;81(12):1405-10. [PubMed] [DARE]

Primary/Secondary Keywords