Parasitic Diseases of Warm Climate: Protozoa and Worms - Related Resources
Cochrane reviews
- Praziquantel and oxamniquine are both effective Drugs for Treating Schistosoma Mansoni-Infection.
- Praziquantel (single dose) appears to be more effective than metrifonate (split dose) in terms of parasitological cure, but the reinfection rate is high with both drugs Interventions for Treating Urinary Schistosomiasis.
- Nitromidazolic agents improve parasite-related outcomes in adults and in children, but there are no studies on the prevention of Chagas disease Trypanocidal Drugs for Chronic Trypanosoma Cruzi Infection.
- Evidence on the effectiveness of albendazole, either alone or in combination with ivermectin or diethylcarbamazine, on lymphatic filariasis is inconclusive Albendazole for Lymphatic Filariasis.
- Ivermectin may be effective in reducing punctate keratitis and iridocyclitis but there is insufficient evidence on its effectiveness in preventing visual acuity loss in onchocercal eye diseaseIvermectine for Onchocerchal Eye Disease.
- Routine deworming of children in endemic areas may not improve average nutritional status, haemoglobin, cognition, school performance, or survivalDeworming Drugs for Treating Soil-Transmitted Intestinal Worms in Children.
- High population coverage of diethylcarbamazine-medicated salt maintained over at least 6 months in a community may be effective at reducing transmission of lymphatic filariasis and may, if maintained over a long enough period, completely interrupt transmission Diethylcarbamazine (Dec)-Medicated Salt for Community-Based Control of Lymphatic Filariasis.
- In Leishmania major infections oral fluconazole, paromomycin methylbenzethonium chloride and photodynamic therapy may be of benefit. In Leishmania tropica infections, itraconazole may be superior to placebo Interventions for Old World Cutaneous Leishmaniasis.
Literature
- Dickson R, Awasthi S, Williamson P, Demellweek C, Garder P. Effect of treatment of intestinal helminth infection on growth and cognitive performance in children: a systematic review of randomised trials. BMJ 2000;320:1697-1701
- Bethony J et al. Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm. Lancet 2006;367:1521-1532
- Brunzell JD. Hypertriglyceridemia. N Engl J Med 2007;357:1009-1017
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