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References
Adverse Effects of Antineoplastic Drugs - Related Resources
Cochrane reviews
Liposomal-encapsulated
doxorubicin
appears to be less cardiotoxic than conventional doxorubicin
Different Anthracycline Derivates for Reducing Cardiotoxicity in Cancer Patients
.
An anthracycline
infusion
duration of six hours
or
longer reduces the
risk
of clinical heart failure
Different Dosage Schedules for Reducing Cardiotoxicity in Cancer Patients Receiving Anthracycline Chemotherapy
.
There are several interventions that are
at
least of some benefit at preventing or reducing the severity of
mucositis
associated with
cancer
treatment, e.g.
amifostine
, antibiotic pastille or paste and hydrolytic enzymes for patients with
head
and neck cancer, and
ice
chips for patients undergoing chemotherapy with 5-FU
Prevention of Oral Mucositis in Patients Receiving Treatment for Cancer
.
Exercise
may have some benefit in the
management
of
fatigue
both during and after cancer treatment
Exercise for the Management of Cancer-Related Fatigue in Adults
.
There is no evidence for or against
antibiotics
compared to granulocyte
colony stimulating factors
(G-CSF) for the
prevention of infection
s in cancer patients undergoing chemotherapy
Prophylactic Antibiotics or G(M)-CSF in Cancer Patients Undergoing Chemotherapy
.
Psychosocial interventions
during cancer treatment may be effective in reducing fatigue
Psychosocial Interventions for Reducing Fatigue during Cancer Treatment
.
Low level
laser treatment
seems to be beneficial in reducing the severity of mucositis, although the evidence is insufficient on interventions for
oral
mucocitis in patients receiving treatment for cancer
Interventions for Oral Mucositis in Patients Receiving Treatment for Cancer
.
5-HT3 antagonists may be more effective than older
antiemetic
agents in
children
who are to receive highly emetogenic chemotherapy. The addition of
dexamethasone
to 5-HT3 antagonists appears to make them even better, although it remains uncertain how the proven benefit of
steroid
in reducing emesis balances with the in vitro
reduction
in chemotherapy
sensitivity
Antiemetic Medication for Prevention and Treatment of Chemotherapy Induced Nausea and Vomiting in Childhood
.
Literature
Hesketh PJ.
Chemotherapy-induced
nausea and vomiting. N Engl J Med 2008 Jun 5;358(23):2482-94.
[PubMed]
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