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References

Male Hypogonadism and Hormone Replacement - Related Resources

OtherEvidence summaries

Clinical guidelines

  • Bhasin S, Brito JP, Cunningham GR ym. Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 2018;103(5):1715-1744. [PubMed]

Literature

  • Travison TG, Vesper HW, Orwoll E et al. Harmonized Reference Ranges for Circulating Testosterone Levels in Men of Four Cohort Studies in the United States and Europe. J Clin Endocrinol Metab 2017;102(4):1161-1173. [PubMed]
  • Ponce OJ, Spencer-Bonilla G, Alvarez-Villalobos N et al. The efficacy and adverse events of testosterone replacement therapy in hypogonadal men: A systematic review and meta-analysis of randomized, placebo-controlled trials. J Clin Endocrinol Metab 2018;103(5):1745-1754. [PubMed]
  • Cunningham GR, Stephens-Shields AJ, Rosen RC et al. Testosterone Treatment and Sexual Function in Older Men With Low Testosterone Levels. J Clin Endocrinol Metab 2016;101(8):3096-104. [PubMed]
  • Snyder PJ, Kopperdahl DL, Stephens-Shields AJ et al. Effect of Testosterone Treatment on Volumetric Bone Density and Strength in Older Men With Low Testosterone: A Controlled Clinical Trial. JAMA Intern Med 2017;177(4):471-479. [PubMed]
  • Cheetham TC, An J, Jacobsen SJ et al. Association of Testosterone Replacement With Cardiovascular Outcomes Among Men With Androgen Deficiency. JAMA Intern Med 2017;177(4):491-499. [PubMed]
  • Alexander GC, Iyer G, Lucas E et al. Cardiovascular Risks of Exogenous Testosterone Use Among Men: A Systematic Review and Meta-Analysis. Am J Med 2017;130(3):293-305. [PubMed]
  • Budoff MJ, Ellenberg SS, Lewis CE et al. Testosterone Treatment and Coronary Artery Plaque Volume in Older Men With Low Testosterone. JAMA 2017;317(7):708-716. [PubMed]
  • Snyder PJ, Bhasin S, Cunningham GR et al. Effects of Testosterone Treatment in Older Men. N Engl J Med 2016;374(7):611-24. [PubMed]
  • Yeap BB, Alfonso H, Chubb SA et al. In older men an optimal plasma testosterone is associated with reduced all-cause mortality and higher dihydrotestosterone with reduced ischemic heart disease mortality, while estradiol levels do not predict mortality. J Clin Endocrinol Metab 2014;99(1):E9-18. [PubMed]
  • Basaria S, Harman SM, Travison TG et al. Effects of Testosterone Administration for 3 Years on Subclinical Atherosclerosis Progression in Older Men With Low or Low-Normal Testosterone Levels: A Randomized Clinical Trial. JAMA 2015;314(6):570-81. [PubMed]
  • Wu FC, Tajar A, Beynon JM et al. Identification of late-onset hypogonadism in middle-aged and elderly men. N Engl J Med 2010;363(2):123-35. [PubMed]
  • Basaria S, Coviello AD, Travison TG et al. Adverse events associated with testosterone administration. N Engl J Med 2010;363(2):109-22. [PubMed]
  • Spitzer M, Huang G, Basaria S et al. Risks and benefits of testosterone therapy in older men. Nat Rev Endocrinol 2013;9(7):414-24. [PubMed]
  • Xu L, Freeman G, Cowling BJ et al. Testosterone therapy and cardiovascular events among men: a systematic review and meta-analysis of placebo-controlled randomized trials. BMC Med 2013;11():108. [PubMed]
  • Vigen R, O'Donnell CI, Barón AE et al. Association of testosterone therapy with mortality, myocardial infarction, and stroke in men with low testosterone levels. JAMA 2013;310(17):1829-36. [PubMed]

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