A systematic review 1 including 482 studies was abstracted in DARE.
Response contingent procedures (e.g. guided movement training) were significantly more effective than antecedent control procedures (e.g. diet)(p<0.001), pharmacology (p<0.001) and response non-contingent procedures (e.g. differential reinforcement of other behaviour) (p<0.001). Response non-contingent procedures were significantly more effective than pharmacology (p<0.001). Behaviours defined as externally destructive tend to be less successfully treated than behaviours defined as internally maladaptive or as socially disruptive.
Comment: The quality of evidence is downgraded by inconsistency (heterogeneity in results in different populations) and imprecise results (few patients, no control groups).
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