A Cochrane review [Abstract] 1 included 7 studies with a total of 4 195 subjects. 5 studies compared adhesive drapes with no drape and 2 studies compared iodine-impregnated adhesive drapes with no drape. A significantly higher proportion of patients in the adhesive drape group developed a surgical site infection when compared with no drape (RR 1.23, 95% CI 1.02 to 1.48; 5 studies, n=3 082). Iodine-impregnated adhesive drapes compared with no drape had no effect on the surgical site infection rate (RR 1.03, 95% CI 0.064 to 1.66; 2 studies, n=1 113).
Comment: The quality of evidence is downgraded by study quality (unclear allocation concealment and lack of blinding of outcome assessment).
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