Human Papillomavirus (HPV) Infection - Related Resources

• 5-Fluorouracil seems to effective for genital warts compared with placebo or podophyllin in non-immunocompromised individuals5-Fluorouracil for Genital Warts.

OtherEvidence summaries

• There is no evidence to support the use of HPV DNA testing as a primary screening tool for cervical cancer or for triaging of women with equivocal cervical screening results Human Papillomavirus Testing Versus Conventional Cytology for Cytological Cervical Lesions.
• Topical interferon appearst to be more effective than placebo for clearance of genital warts Topical Interferon for Genital Warts.
• The HPV-16/18 L1 virus-like particle vaccine induces a high degree of protection against HPV-16/18 infection and associated cervical lesions as compared with placebo, and is safe HPV Vaccines Against Human Papillomavirus.
• In women positive for HPV DNA, HPV-16/18 vaccination appears not to accelerate clearance of the virus Effect of Human Papillomavirus 16/18 L1 Virus Like Particle Vaccine Among Women with Pre-Existing Infection.

• Centers for Disease Control and Prevention. Sexually Transmitted Diseases Treatment Guidelines, 2015: Recommendations and Reports. June 5, 2015 / 64(RR3);1-137http://www.cdc.gov/mmwr/preview/mmwrhtml/rr6403a1.htm.

• Buck HW. Warts (genital). BMJ Clin Evid. 2010; 2010: 1602.

Literature

• Kahn JA. HPV vaccination for the prevention of cervical intraepithelial neoplasia. N Engl J Med 2009 Jul 16;361(3):271-8. [PubMed]
• Schiffman M, Castle PE, Jeronimo J, Rodriguez AC, Wacholder S. Human papillomavirus and cervical cancer. Lancet 2007 Sep 8;370(9590):890-907 [PubMed]