Recurrent Miscarriage - Related Resources

Cochrane reviews

Human chorionic gonadotrophin might not be effective for preventing further miscarriage in women with a history of unexplained recurrent miscarriage compared with placebo or no treatment, although the evidence is insufficient Human Chorionic Gonadotrophin (Hcg) for Preventing Recurrent Miscarriage.
Cervical cerclage appears not to reduce pregnancy loss and preterm delivery rates in women at low or medium risk of mid trimester loss .
Cervical cerclage appears to reduce the incidence of preterm birth compared with no treatment in women at risk of recurrent preterm birth, without statistically significant reduction in perinatal mortality or neonatal morbidity Cervical Stitch (Cerclage) for Preventing Preterm Birth in Singleton Pregnancy.
Aspirin or anticoagulants may not be effective for the treatment of recurrent pregnancy loss in women with or without antiphospholipid syndrome Aspirin or Anticoagulants for the Treatment of Recurrent Pregnancy Loss in Women Without Antiphospholipid Syndrome.
There is insufficient evidence on the effects of bed rest in the prevention of miscarriage. Bed Rest during Early Pregnancy for Preventing Miscarriage.
Routine councelling after a miscarriage may not be effective for improving psychological well being Follow-Up for Improving Psychological Well Being for Women after a Miscarriage.

Bates SM, Greer IA, Pabinger I et al. Venous thromboembolism, thrombophilia, antithrombotic therapy, and pregnancy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008;133(6 Suppl):844S-886S. [PubMed]
Royal College of Obstetricians and Gynaecologists. The investigation and treatment of couples with recurrent miscarriage. Guideline No 17, May 2003 http://www.gfmer.ch/Endo/Course2003/Infertility/Recurrent_Miscarriage_No17.pdf

Hatasaka HH. Recurrent miscarriage: epidemiologic factors, definitions, and incidence. Clin Obstet Gynecol 1994 Sep;37(3):625-34. [PubMed]
Clifford K, Rai R, Regan L. Future pregnancy outcome in unexplained recurrent first trimester miscarriage. Hum Reprod 1997 Feb;12(2):387-9. [PubMed]
Rai R, Regan L. Recurrent miscarriage. Lancet 2006 Aug 12;368(9535):601-11. [PubMed]
Jauniaux E, Farquharson RG, Christiansen OB, Exalto N. Evidence-based guidelines for the investigation and medical treatment of recurrent miscarriage. Hum Reprod 2006 Sep;21(9):2216-22. [PubMed]
Bates SM, Greer IA, Pabinger I, Sofaer S, Hirsh J, American College of Chest Physicians. Venous thromboembolism, thrombophilia, antithrombotic therapy, and pregnancy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008 Jun;133(6 Suppl):844S-886S. [PubMed]

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