Polyneuropathies - Related Resources

Cochrane reviews

Corticosteroids seem to have limited effect in the short term in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Standard-dose daily oral corticosteroid (prednisolone) seems to be as beneficial as high-dose oral corticosteroid (dexamethasone), although the evidence is insufficientCorticosteroids for Chronic Inflammatory Demyelinating Polyradiculoneuropathy.
There is insufficient evidence to decide whether azathioprine or interferon beta is beneficial in chronic inflammatory demyelinating polyradiculoneuropathy Azathioprine, Interferon Beta-1a or Methotrexate for Chronic Inflammatory Demyelinating Polyradiculoneuropathy.
Plasma exchange may provide significant short-term benefit for patients with chronic inflammatory demyelinating polyradiculoneuropathy but rapid deterioration may occur afterwards Plasma Exchange for Chronic Inflammatory Demyelinating Polyradiculoneuropathy.
Intravenous immunoglobulin (IVIg) may improve disability in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), having probably similar efficacy to plasma exchange and oral prednisolone Intravenous Immunoglobulin (Ivig) for Chronic Inflammatory Demyelinating Polyradiculoneuropathy (Cidp).
There is insufficient evidence on longer-term benefits of immunotherapies in anti-myelin associated glycoprotein paraproteinaemic peripheral neuropathy Immunotherapy for Igm Anti-Myelin-Associated Glycoprotein Paraprotein-Associated Peripheral Neuropathies.
In multifocal motor neuropathy mycophenolate mofetil might possibly not be beneficial. There is no evidence from randomised controlled trials of other immunosuppressive treatments Immunosuppressive Treatment for Multifocal Motor Neuropathy.
Ascorbic acid does not improve the course of Charcot-Marie-Tooth disease type 1A in adults or children. Ascorbic Acid for the Treatment of Charcot-Marie-Tooth Disease.
There is insufficient evidence on interventions for increasing ankle range of motion in Charcot-Marie-Tooth disease type 1A or Duchenne muscular dystrophy Interventions for Increasing Ankle Range of Motion in Patients with Neuromuscular Disease.
An exercise programme seems to increase the ability to walk in patients with Charcot-Marie-Tooth disease, although the evidence is insufficient Rehabilitation for Foot Drop in Neuromuscular Disease.

Other Internet resources

Hereditary neuropathy with liability to pressure palsies. Orphanet ORPHA640 http://www.orpha.net/consor/cgi-bin/Disease_Search.php?lng=EN&data_id=192&Disease_Disease_Search_diseaseGroup=Hereditary-neuropathy-with-liability-to-pressure-palsies&Disease_Disease_Search_diseaseType=Pat&Disease(s) concerned=Hereditary-neuropathy-with-l
Multifocal motor neuropathy with conduction block. Orphanet ORPHA641 http://www.orpha.net/consor/cgi-bin/Disease_Search.php?lng=EN&data_id=8714

Literature

Rutkove SB. A 52-year-old woman with disabling peripheral neuropathy: review of diabetic polyneuropathy. JAMA 2009 Oct 7;302(13):1451-8. [PubMed]
Winer JB. Guillain-Barré syndrome. BMJ 2008 Jul 17;337():a671. [PubMed]
England JD, Gronseth GS, Franklin G et al; American Academy of Neurology. Practice Parameter: evaluation of distal symmetric polyneuropathy: role of autonomic testing, nerve biopsy, and skin biopsy (an evidence-based review). Report of the American Academy of Neurology, American Association of Neuromuscular and Electrodiagnostic Medicine, and American Academy of Physical Medicine and Rehabilitation. Neurology 2009 Jan 13;72(2):177-84. [PubMed]

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Polyneuropathies - Related Resources

Cochrane reviews

Other Internet resources

Literature