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Indications

REMS

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

GI: nausea.

Neuro: high dose:dizziness, sedation.

Interactions

Drug-Drug:

Availability

(Generic available)

Route/Dosage

US Brand Names

Creo-Terpin, Creomulsion Adult Formula, Creomulsion for Children, Delsym, Father John's, Hold DM, Pediacare Children's Long-Acting Cough, Robafin Cough, Robitussin Children's Cough Long-Acting, Robitussin Cough Long-Acting, Robitussin CoughGels Long-Acting, Robitussin Lingering Cold Long-Acting CoughGels, Scot-Tussin Diabetes, Triaminic Thin Strips Children's Long-Acting Cough, Triaminic Children's Cough Long-Acting, Vicks 44 Cough Relief, Vicks DayQuil Cough, Vicks Nature Fusion Cough

Action

Therapeutic Effects:

Classifications

Therapeutic Classification: allergy, cold and cough remedies, antitussives

Pharmacokinetics

Absorption: Rapidly absorbed from the GI tract. Extended-release product is slowly absorbed.

Distribution: Unknown. Probably crosses the placenta and enters breast milk.

Metabolism/Excretion: Metabolized to dextrorphan, an active metabolite. Dextromethorphan and dextrorphan are renally excreted.

Half-life: Unknown.

Canadian Brand Names

Balminil DM, Benylin DM, Bronchophan Forte DM, Buckley's DM, Cough Syrup DM, Delsym DM, DM Children's Cough Syrup, DM Cough Syrup, Dry Cough Syrup, Koffex DM, Neocitran Thin Strips Cough, Sedatuss DM, Sucrets Cough Control, Sucrets DM, Triaminic DM, Triaminic Long-Acting Cough, Vicks Custom Care Dry Cough

Time/Action Profile

(cough suppression)

ROUTEONSETPEAKDURATION
PO15–30 minunknown3–6 hr
PO-ERunknownunknown9–12 hr

†Up to 8 hr for gelcaps.

Patient/Family Teaching

Pronunciation

dex-troe-meth-OR-fan