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Indications

REMS

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

CV: chest pain.

Derm: pruritus.

EENT: conjunctivitis.

GI: abdominal pain, constipation, dyspepsia, flatulence, liver enzymes, nausea, vomiting.

GU: urinary tract infection, vaginitis.

MS: arthralgia, myalgia, neck pain.

Neuro: headache, agitation, aggression, anxiety, depression, dizziness, dream abnormalities, hallucinations, hypertonia, insomnia, irritability, malaise, nervousness, restlessness, somnolence, SUICIDAL THOUGHTS, tremor, weakness.
Misc: fever, lymphadenopathy.

Interactions

Drug-Drug:

Drug-Food:

Availability

(Generic available)

Route/Dosage

US Brand Names

Zyflo, Zyflo CR

Action

Therapeutic Effects:

Classifications

Therapeutic Classification: bronchodilators

Pharmacologic Classification:

Pharmacokinetics

Absorption: Rapidly absorbed following oral administration.

Distribution: Unknown.

Protein Binding: 93%.

Metabolism/Excretion: Mostly metabolized by the liver.

Half-life: 2.5 hr.

Time/Action Profile

(improvement in pulmonary function)

ROUTEONSETPEAKDURATION
POunknown1.7 hrunknown

Patient/Family Teaching

Pronunciation

zye-LOO-ton