prasterone

REMS

Contraindicated in:

Use Cautiously in:

GU: vaginal discharge

Drug-drug:

Intrarosa

Inactive steroid that is converted into active androgens and/or estrogens. Exact mechanism in treatment of vulvar and vaginal atrophy in menopausal women not fully established.

Therapeutic effects:

Therapeutic Classification: none assigned

Pharmacologic Classification: steroids

Absorption: Unknown.

Distribution: Unknown.

Metabolism/Excretion: Metabolized via dehydrogenase, reductase, and aromatase to estradiol and testosterone.

Half-Life: Unknown.

(reduction in severity of dyspareunia)

ROUTE	ONSET	PEAK	DURATION
Vag	unknown	12 wk	unknown

Explain purpose of prasterone to patient. Instruct patient to read Instructions for Use before inserting prasterone.
Inform patient that vaginal discharge and abnormal PAP smear findings may occur with prasterone.
Advise patient to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken and to consult with health care professional before taking other medications during therapy.

PRAS-ter-one