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Indications

REMS

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

EENT: epistaxis, nasal burning, nasal irritation, nasopharyngeal fungal infection, otitis media, pharyngitis, rhinitis, sinusitis, sneezing.

Endo: adrenal suppression (high-dose, long-term therapy only).

GI: vomiting.

Neuro: headache.

Resp: cough.

Interactions

Drug-Drug:

Availability

Route/Dosage

US Brand Names

Nasacort Allergy 24 HR

Action

Therapeutic Effects:

Classifications

Therapeutic Classification: corticosteroids

Pharmacokinetics

Absorption: Action of all agents is primarily local after nasal use.

Distribution: Crosses the placenta and enters breast milk in small amounts.

Metabolism/Excretion: Rapidly and extensively metabolized by the liver; 40% excreted in urine, 60% in feces.

Half-life: 3–5.4 hr.

Canadian Brand Names

Nasacort AQ

Time/Action Profile

(improvement in symptoms)

ROUTEONSETPEAKDURATION
Intranasalfew days3–4 daysunknown

Patient/Family Teaching

Pronunciation

trye-am-SIN-oh-lone