zoster vaccine, live

Contraindicated in:

History of anaphylactic/anaphylactoid reactions to gelatin, neomycin, or other vaccine components;
Primary/acquired immunodeficiency states (including leukemia, lymphoma, AIDS);
Concurrent immunosupressive medications (including high dose corticosteroids);
Acute febrile illness (>38.5° C or 101.3° F;
Active untreated tuberculosis;
OB: Pregnancy;
Pedi: Children.

Use Cautiously in:

OB: Child-bearing potential (pregnancy should be avoided for 3 mo following vaccination);
OB: Lactation.

Adv. Reactions/Side Effects ⬆ ⬇

Local: swelling, redness, pain, swelling

Interactions ⬆ ⬇

Drug-drug:

Concurrent immunosupressants including antineoplastics and high dose corticosteroids may ↓ response to and ↑ risk of adverse reactions.
Pneumococcal vaccine (Pneumovax 23) may ↓ response; do not administer concomitantly.

Availability ⬆ ⬇

Lyophylized powder for injection (with diluent): at least 19,400 PFU/0.65 mL

Route/Dosage ⬆ ⬇

US Brand Names ⬆ ⬇

Action ⬆ ⬇

Therapeutic effects:

Classifications ⬆ ⬇

Therapeutic Classification: vaccines/immunizing agents

Pharmacologic Classification: active immunizer

Pharmacokinetics ⬆ ⬇

Absorption: Well absorbed following subcut administration.

Distribution: Unknown.

Metabolism/Excretion: Unknown.

Half-Life: Unknown.

Time/Action Profile ⬆ ⬇

ROUTE	ONSET	PEAK	DURATION
SC	unknown	unknown	unknown

Patient/Family Teaching ⬆ ⬇

Explain purpose of vaccine to patient. Provide patient with a copy of the Patient Information Sheet.
Advise patient to notify health care professional if pregnancy is planned or expected. Pregnancy should be avoided for 3 mo after administration of vaccine.