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Indications

High Alert

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

Side effects primarily caused by LHRH antagonist

CV: edema, hypertension.

Derm: photosensitivity, rash.

Endo: gynecomastia, hot flushes.

GI: diarrhea, nausea, vomiting, HEPATOTOXICITY.

GU: erectile dysfunction, loss of libido.

Neuro: anxiety, confusion, drowsiness, mental depression, nervousness.

Interactions

Drug-Drug:

Availability

(Generic available)

Route/Dosage

US Brand Names

Eulexin

Action

Therapeutic Effects:

Classifications

Therapeutic Classification: antineoplastics

Pharmacologic Classification: antiandrogens

Pharmacokinetics

Absorption: Well absorbed after oral administration.

Distribution: Unknown.

Metabolism/Excretion: Mostly metabolized by the liver. Some conversion to another antiandrogenic compound (2-hydroxyflutamide).

Half-life: Unknown.

Time/Action Profile

ROUTEONSETPEAKDURATION
POunknownunknownunknown

Patient/Family Teaching

Pronunciation

FLOO-ta-mide