section name header

Indications

REMS

Betapace AF and Sotylize:

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

CV: ARRHYTHMIAS, BRADYCARDIA, HF, orthostatic hypotension.

Derm: itching, rash.

EENT: blurred vision, dry eyes, nasal stuffiness.

Endo: hyperglycemia, hypoglycemia.

GI: constipation, diarrhea, nausea.

GU: erectile dysfunction, libido.

MS: arthralgia, back pain, muscle cramps.

Neuro: fatigue, weakness, anxiety, depression, dizziness, drowsiness, insomnia, memory loss, mental status changes, nervousness, nightmares, paresthesia.

Resp: bronchospasm, PULMONARY EDEMA, wheezing.

Interactions

Drug-Drug:

Availability

(Generic available)

Route/Dosage

Ventricular Arrhythmias

Renal Impairment

Atrial Fibrillation/Atrial Flutter

Renal Impairment

US Brand Names

Betapace, Betapace AF, Sorine, Sotylize

Action

Therapeutic Effects:

Classifications

Therapeutic Classification: antiarrhythmics (class III)

Pharmacokinetics

Absorption: Well absorbed following oral administration.

Distribution: Widely distributed to tissues.

Metabolism/Excretion: Primarily excreted as unchanged drug in the urine.

Half-life: 12 hr ( in renal impairment).

Time/Action Profile

(antiarrhythmic effects)

ROUTEONSETPEAKDURATION
POhr2–3 days8–12 hr

Patient/Family Teaching

Pronunciation

SOE-ta-lol