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Indications

High Alert


Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

Side effects primarily caused by LHRH antagonist

Interactions

Drug-drug:

Availability

(Generic available)

Route/Dosage

US Brand Names

Eulexin

Action

  • Antagonizes the effects of androgen (testosterone) at the cellular level.
Therapeutic effects:
  • Decreased growth of prostate carcinoma, an androgen-sensitive tumor.

Classifications

Therapeutic Classification: antineoplastics

Pharmacologic Classification: antiandrogens

Pharmacokinetics

Absorption: Well absorbed after oral administration.

Distribution: Unknown.

Metabolism/Excretion: Mostly metabolized by the liver. Some conversion to another antiandrogenic compound (2-hydroxyflutamide).

Half-Life: Unknown.

Time/Action Profile

ROUTEONSETPEAKDURATION
POunknownunknownunknown



Patient/Family Teaching

Pronunciation

FLOO-ta-mide