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Indications

REMS

Unlabeled Uses:

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

Derm: pruritus, rash.

Endo: hyperglycemia (with suspension).

GI: constipation, diarrhea, dry mouth, gastric discomfort, indigestion, nausea.

Neuro: dizziness, drowsiness.
Misc: (INCLUDING ANAPHYLAXIS AND ANGIOEDEMA)HYPERSENSITIVITY REACTIONS .

Interactions

Drug-Drug:

Availability

(Generic available)

Route/Dosage

Treatment of Ulcers

Gastroesophageal Reflux

Stomatitis

Proctitis

US Brand Names

Carafate

Action

Therapeutic Effects:

Classifications

Therapeutic Classification: antiulcer agents

Pharmacologic Classification: gi protectants

Pharmacokinetics

Absorption: Systemic absorption is minimal (<5%).

Distribution: Unknown.

Metabolism/Excretion: >90% is eliminated in the feces.

Half-life: 6–20 hr.

Canadian Brand Names

Cytogard, Sulcrate, Sulcrate Plus

Time/Action Profile

(mucosal protectant effect)

ROUTEONSETPEAKDURATION
PO1–2 hrunknown6 hr

Patient/Family Teaching

Pronunciation

soo-KRAL-fate