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Indications

REMS

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

EENT: conjunctivitis.

GI: diarrhea, nausea, abdominal pain, anorexia, dry mouth, PANCREATITIS, weight loss.

Local: injection site reactions.

MS: limb pain, myalgia.

Neuro: fatigue.

Resp: cough, pneumonia, sinusitis.
Misc: herpes simplex, hypersensitivity reactions, immune reconstitution syndrome.

Interactions

Drug-Drug:

Availability

Route/Dosage

see Calculator

US Brand Names

Fuzeon

Action

Therapeutic Effects:

Classifications

Therapeutic Classification: antiretrovirals

Pharmacologic Classification: fusion inhibitors

Pharmacokinetics

Absorption: 84% absorbed following SUBQ administration.

Distribution: 5.5 L.

Protein Binding: 92% bound to plasma proteins.

Metabolism/Excretion: Broken down into component amino acids and then recycled in body pool.

Half-life: 3.8 hr.

Time/Action Profile

(blood levels)

ROUTEONSETPEAKDURATION
SUBQUnknown8 hr12 hr

Patient/Family Teaching

Pronunciation

en-FOO-veer-tide