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Indications

High Alert

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

Noted for patients receiving heparin and aspirin in addition to eptifibatide

CV: hypotension.

Hemat: BLEEDING (INCLUDING GI AND INTRACRANIAL BLEEDING, HEMATURIA, AND HEMATOMAS), thrombocytopenia.

Interactions

Drug-Drug:

Drug-Natural Products:

Availability

(Generic available)

Route/Dosage

see Calculator

Acute Coronary Syndrome

Renal Impairment

Percutaneous Coronary Intervention

Renal Impairment

US Brand Names

Integrilin

Action

Therapeutic Effects:

Classifications

Therapeutic Classification: antiplatelet agents

Pharmacologic Classification: glycoprotein iib iiia inhibitors

Pharmacokinetics

Absorption: IV administration results in complete bioavailability.

Distribution: Unknown.

Metabolism/Excretion: 50% excreted by the kidneys.

Half-life: 2.5 hr.

Time/Action Profile

(effects on platelet function)

ROUTEONSETPEAKDURATION
IVimmediatefollowing bolusbrief

†Inhibition is reversible following cessation of infusion.

Patient/Family Teaching

Pronunciation

ep-ti-FIB-a-tide