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Indications ⬇

REMS


Contraind./Precautions ⬆ ⬇

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects ⬆ ⬇

EENT: nasal burning, rebound nasal congestion (if used for >3 days), sneezing

Interactions ⬆ ⬇

Drug-drug:

Availability ⬆ ⬇

Route/Dosage ⬆ ⬇

US Brand Names ⬆ ⬇

Afrin, Vicks Sinex

Action ⬆ ⬇

  • Stimulates alpha-1 adrenergic receptors in the arterioles of the nasal mucosa, leading to vasoconstriction.
Therapeutic effects:
  • Reduction of nasal congestion and sinus congestion/pressure.

Classifications ⬆ ⬇

Therapeutic Classification: decongestants/vasoconstrictors

Pharmacologic Classification: adrenergics

Pharmacokinetics ⬆ ⬇

Absorption: Unknown.

Distribution: Unknown.

Metabolism/Excretion: Unknown.

Half-Life: Unknown.

Time/Action Profile ⬆ ⬇

(reduction of nasal congestion)

ROUTEONSETPEAKDURATION
Intranasalwithin 10 minunknownup to 12 hr



Patient/Family Teaching ⬆ ⬇

Pronunciation ⬆

oxs-ee-met-AZ-oh-leen