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Indications

REMS

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

EENT: nasopharyngitis, pharyngolaryngeal pain.

GI: constipation, dyspepsia, nausea.

GU: urinary tract infection.

MS: back pain.

Neuro: dizziness, headache, insomnia, multiple sclerosis relapse, paresthesia, SEIZURES, vertigo, weakness.
Misc: ANAPHYLAXIS.

Interactions

Drug-Drug:

Availability

(Generic available)

Route/Dosage

US Brand Names

Ampyra

Action

Therapeutic Effects:

Classifications

Therapeutic Classification: anti-multiple sclerosis agents

Pharmacologic Classification:

Pharmacokinetics

Absorption: Rapidly and completely absorbed (96%).

Distribution: Unknown.

Metabolism/Excretion: 96% eliminated in urine, 0.5% in feces.

Half-life: 5.2–6.5 hr.

Canadian Brand Names

Fampyra

Time/Action Profile

(improvement in walking speed)

ROUTEONSETPEAKDURATION
POunknown3–4 hr24 hr

Patient/Family Teaching

Pronunciation

dal-FAM-pri-deen