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Indications

REMS


Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

None significant.

Interactions

Drug-drug:

  • None significant.

Availability

(Generic available)
  • Chewable tablets: 40 mgOTC; 80 mgOTC; 125 mgOTC; 150 mgOTC
  • Tablets: 60 mgOTC; 80 mgOTC; 95 mgOTC
  • Capsules: 125 mgOTC; 166 mgOTC; 180 mgOTC
  • Drops: 40 mg/0.6 mLOTC; 40 mg/mLOTC; 95 mg/1.425 mLOTC
  • In combination with: antacidsOTC. See Appendix [not included in this PDA edition].

Route/Dosage

  • PO (Adults ): 40–125 mg qid, after meals and at bedtime (up to 500 mg/day).
  • PO (Children 2–12 yr): 40 mg 4 times daily.
  • PO (Children <2 yr): 20 mg 4 times daily (up to 240 mg/day).

US Brand Names

Degas, Extra Strength Gas-X, Flatulex, Gas-X, Genasyme, Maximum Strength Mylanta Gas, Mylanta Gas, Mylicon, Phazyme

Action

  • Causes the coalescence of gas bubbles.
  • Does not prevent the formation of gas.
Therapeutic effects:
  • Passage of gas through the GI tract by belching or passing flatus.

Classifications

Therapeutic Classification: antiflatulent

Pharmacokinetics

Absorption: No systemic absorption occurs.

Distribution: Not systemically distributed.

Metabolism/Excretion: Excreted unchanged in the feces.

Half-Life: Unknown.

Canadian Brand Names

Gas Relief, Infacol, Ovol, Pediacol

Time/Action Profile

(antiflatulent effect)

ROUTEONSETPEAKDURATION
POimmediateunknown3 hr



Patient/Family Teaching

  • Explain to patient the importance of diet and exercise in the prevention of gas. Also explain that this medication does not prevent the formation of gas.
  • Advise patient to notify health care professional if symptoms are persistent.

Pronunciation

si-METH-i-kone