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Indications

REMS

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

CV: hypotension.

GI: abdominal pain, diarrhea ( in females and elderly), dyspepsia, reflux.

GU: acute renal failure.

Resp: cough.
Misc: ANGIOEDEMA.

Interactions

Drug-Drug:

Drug-Food:

Availability

(Generic available)

Route/Dosage

US Brand Names

Tekturna

Action

Therapeutic Effects:

Classifications

Therapeutic Classification: antihypertensives

Pharmacologic Classification:

Pharmacokinetics

Absorption: Poorly absorbed (bioavailability 2.5%).

Distribution: Unknown.

Metabolism/Excretion: 2% excreted unchanged in urine, remainder is probably metabolized (CYP3A4 enzyme system).

Half-life: 24 hr.

Canadian Brand Names

Rasilez

Time/Action Profile

(antihypertensive effect)

ROUTEONSETPEAKDURATION
POunknown2 wk24 hr

Patient/Family Teaching

Pronunciation

a-LIS-ki-ren