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Indications

Complementary/Alternative Medicine: This monograph describes a natural or herbal product that is not subject to FDA guidelines for medicines. Patients and clinicians are advised to read package labels carefully to ensure safe and efficacious use.

REMS


Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

CNS: "Post-Feverfew Syndrome" (anxiety, headache, insomnia, muscle and joint aches)

CV: with long-term usetachycardia

GI: diarrhea, heartburn, mouth ulceration and soreness (from chewing fresh leaves), nausea, vomiting

Derm: contact dermatitis (when used topically)

Interactions

Natural-Drug Products:

Natural-Natural Products:

Availability

Route/Dosage

US Brand Names

Altamisa, Bachelor's Buttons, Chrysanthemum parethenium, Featerfoiul, Featherfew, Featherfoil, Flirtwort Midsummer Daisy, Pyrethrum parthenium, Santa Maria, Tanaceti parthenii, Wild chamomile, Wild quinine

Action

  • The sesquiterpene lactone, parthenolide, may provide feverfew's migraine prophylaxis effects.
  • Feverfew may also have antiplatelet and vasodilatory effects and block prostaglandin synthesis.
Therapeutic effects:
  • May reduce the symptoms and frequency of migraine headaches.

Classifications

Therapeutic Classification: vascular headache suppressants

Pharmacokinetics

Absorption: Unknown.

Distribution: Unknown.

Metabolism/Excretion: Unknown.

Half-Life: Unknown.

Time/Action Profile

ROUTEONSETPEAKDURATION
PO2–4 mounknownunknown

Patient/Family Teaching

Pronunciation

FEE-vurr-fyoo