PO (Adults ): 250 mg every 12 hr (up to 250 mg three times daily has been used).
US Brand Names⬆⬇
Limbrel
Action⬆⬇
Anti-inflammatory and analgesic properties related to inhibition of prostaglandin synthesis by inhibiting cyclo-oxygenase (not COX-2 selective) and other mediators of inflammation.
Therapeutic effects:
Decreased pain/inflammation associated with osteoarthritis, with improved mobility.
Classifications⬆⬇
Therapeutic Classification: nonopioid analgesics
Pharmacologic Classification: flavanoids
Pharmacokinetics⬆⬇
Absorption: Some intestinal conversion prior to absorption, remainder unknown.
Distribution: Unknown.
Metabolism/Excretion: Mostly metabolized by the liver.
Half-Life: Unknown.
Time/Action Profile⬆⬇
(analgesic effect)
ROUTE
ONSET
PEAK
DURATION
PO
within 1–2 hr
unknown
12 hr
Patient/Family Teaching⬆⬇
Instruct patient to take flavocoxid as directed. Do not increase does without consulting health care professional.
