turmeric

Complementary/Alternative Medicine: This monograph describes a natural or herbal product that is not subject to FDA guidelines for medicines. Patients and clinicians are advised to read package labels carefully to ensure safe and efficacious use.

REMS

Dyspepsia.Osteoarthritis.
Pruritus.

Contraind./Precautions ⬆ ⬇

Contraindicated in:

Hypersensitivity;
Gallbladder disease;
Active GI ulcers.

Use Cautiously in:

Diabetes;
Coagulation disorders;
Liver disease;
OB: Safety not established in pregnancy;
Lactation: Safety not established in breastfeeding;
Pedi: Safety and effectiveness not established in children.

Adv. Reactions/Side Effects ⬆ ⬇

GI: diarrhea, nausea, vomiting

Neuro: dizziness

Interactions ⬆ ⬇

Natural-Drug Products:

May ↑ risk of bleeding with antiplatelet agents and anticoagulants.
May ↓ effectiveness of some cancer medications, including alkylating agents, topoisomerase I inhibitors, and tamoxifen.
May interfere with the glucose-lowering effects of hypoglycemic agents and cause hypoglycemia.
Large amounts of turmeric may ↓ effectiveness of estrogen.

Natural-Natural Products:

May ↑ risk of bleeding with herbs that have antiplatelet/anticoagulant properties, such as clove, garlic, ginger, gingko, and ginseng.
Avoid using with other with herbs that affect blood glucose, such as chromium, fenugreek, garlic, and ginseng.

Availability ⬆ ⬇

Capsules: ^OTC
Tablets: ^OTC

Route/Dosage ⬆ ⬇

PO (Adults ): 1–2 g/day.

US Brand Names ⬆ ⬇

curcuma, curcumin, curcuminoid, turmeric root

Action ⬆ ⬇

Spice that contains a chemical called curcumin, which may ↓ swelling and provide pain relief.

Therapeutic effects:

Decreased inflammation.
Decreased pain.

Classifications ⬆ ⬇

Therapeutic Classification: anti-inflammatories

Pharmacokinetics ⬆ ⬇

Absorption: Unknown.

Distribution: Unknown.

Metabolism/Excretion: Unknown.

Half-Life: Unknown.

Time/Action Profile ⬆ ⬇

	ONSET	PEAK	DURATION
PO	unknown	unknown	unknown

Patient/Family Teaching ⬆ ⬇

Explain purpose and side effects of herb to patient.
Advise patient to consult with health care provider before using any herbal supplement, especially when taken concurrently with Rx or OTC medications or vitamins.
Advise patient to report worsening symptomatology promptly to health care provider.
Advise patient to notify health care provider of signs of bleeding (gums, nosebleeds, unexplained bruising).
Rep: Advise women of reproductive potential to notify health care provider if pregnancy is planned or suspected or if breastfeeding before using this herb.

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Indications ⬇