Treatment of a variety of cutaneous fungal infections, including tinea pedis (athlete’s foot), tinea cruris (jock itch), and tinea corporis (ringworm).
Contraind./Precautions⬆⬇
Contraindicated in:
Hypersensitivity to active ingredients, additives, preservatives, or bases;
Some products contain alcohol and should be avoided in patients with known intolerance.
Use Cautiously in:
Nail and scalp infections (may require additional systemic therapy);
OB: Safety not established.
Adv. Reactions/Side Effects⬆⬇
Local: burning, itching, local hypersensitivity reactions, redness, stinging
Interactions⬆⬇
Drug-drug:
Not known.
Availability⬆⬇
(Generic available)
Cream: 1%
Gel: 1%
Spray liquid: 1%
Route/Dosage⬆⬇
(Adults and Children ≥12 yr): Apply twice daily for 1 wk for tinea pedis. Apply once daily for 1 wk for tinea cruris or tinea corporis.
US Brand Names⬆⬇
Lamisil AT
Action⬆⬇
Affects the synthesis of the fungal cell wall.
Therapeutic effects:
Decrease in symptoms of fungal infection.
Classifications⬆⬇
Therapeutic Classification: antifungals (topical)
Pharmacokinetics⬆⬇
Absorption: Absorption through intact skin is minimal.
Distribution: Distribution after topical administration is primarily local.
Metabolism/Excretion: Highly metabolized; excreted in urine (primarily as metabolites).
Instruct patient to apply medication as directed for full course of therapy, even if feeling better. Emphasize the importance of avoiding the eyes.
Caution patient that some products may stain fabric, skin, or hair. Check label information. Fabrics stained from cream can usually be cleaned by handwashing with soap and warm water.
Patients with athlete’s foot should be taught to wear well-fitting, ventilated shoes, to wash affected areas thoroughly, and to change shoes and socks at least once a day.
Advise patient to report increased skin irritation or lack of response to therapy to health care professional.