lycopene

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Indications ⬇

Complementary/Alternative Medicine: This monograph describes a natural or herbal product that is not subject to FDA guidelines for medicines. Patients and clinicians are advised to read package labels carefully to ensure safe and efficacious use.

REMS

Atherosclerosis prevention.
Exercise-induced asthma.
Cancer prevention.
Oral leukoplakia.

Contraind./Precautions ⬆ ⬇

Contraindicated in:

Hypersensitivity.

Use Cautiously in:

Pregnancy and lactation (when using amounts greater than those found in foods)

Adv. Reactions/Side Effects ⬆ ⬇

GI: abdominal pain, diarrhea, flatulence

Interactions ⬆ ⬇

Natural-Drug Products:

None.

Natural-Natural Products:

Absorption may be increased with beta carotene.

Availability ⬆ ⬇

Softgels: 10 mg, 15 mg, 20 mg

Route/Dosage ⬆ ⬇

PO (Adults ): Exercise-induced asthma: 30 mg/day; Prostate cancer: 15 mg twice daily;Oral leukoplakia: 4–8 mg/day.

US Brand Names ⬆ ⬇

all-trans lycopene, psi-psi-carotene

Action ⬆ ⬇

Lycopene is a predominant carotenoid in blood and tissues that has antioxidant properties. It scavenges free radicals and prevents oxidative damage to DNA. It may decrease cholesterol synthesis and remove LDL cholesterol from circulation. 85% of dietary lycopene comes from tomato-derived products.

Therapeutic effects:

Atherosclerosis prevention.
Cancer prevention.

Classifications ⬆ ⬇

Therapeutic Classification: antioxidants, cardioprotective agents, antineoplastics

Pharmacokinetics ⬆ ⬇

Absorption: Unknown

Distribution: Unknown

Metabolism/Excretion: Unknown

Half-Life: Unknown

Time/Action Profile ⬆ ⬇

	ONSET	PEAK	DURATION
PO	unknown	unknown	unknown

Patient/Family Teaching ⬆ ⬇

Instruct patient to take as directed.
Advise female patient to notify health care professional if pregnancy is planned or suspected or if breastfeeding.

Pronunciation ⬆

LAHY-kuh-peen