(Adults and Children ): Apply once daily in patients with tinea pedis (for 1 mo), tinea cruris (for 2 wk), tinea corporis (for 2 wk), and tinea versicolor (for 2 wk). Apply twice daily in patients with cutaneous candidiasis (for 2 wk).
US Brand Names⬆⬇
Ecoza
Action⬆⬇
Affects the permeability of the fungal cell wall, allowing leakage of cellular contents.
Therapeutic effects:
Decrease in symptoms of fungal infection.
Classifications⬆⬇
Therapeutic Classification: antifungals (topical)
Pharmacokinetics⬆⬇
Absorption: Absorption through intact skin is minimal.
Distribution: Distribution after topical administration is primarily local.
Metabolism/Excretion: Metabolism in the liver and <1% excreted in the urine and feces.
Half-Life: Not applicable.
Time/Action Profile⬆⬇
ROUTE
ONSET
PEAK
DURATION
Top
unknown
unknown
unknown
Patient/Family Teaching⬆⬇
Explain the purpose and side effects of econazole. Instruct patient to apply medication as directed for full course of therapy, even if feeling better. Emphasize the importance of avoiding the eyes and vagina. Advise patient to read Patient Information before starting and with each Rx refill in case of changes.
Caution patient that some products may stain fabric, skin, or hair. Check label information. Fabrics stained from cream can usually be cleaned by handwashing with soap and warm water.
Caution patient that product is flammable and to avoid fire, flame, and smoking during and immediately following application.
Patients with athlete’s foot should be taught to wear well-fitting, ventilated shoes, to wash affected areas thoroughly, and to change shoes and socks at least once a day.
Advise patient to report ↑ skin irritation or lack of response to therapy to health care professional.
Advise patient that early relief of symptoms may be seen in 2–3 days. For Candida, tinea cruris, tinea corporis, and tinea versicolor, 2 wk are needed, and for tinea pedis, therapeutic response may take 4 wk. Recurrent fungal infections may be a sign of systemic illness.
Advise patient to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken and to consult with health care professional before taking other medications.
Rep: Advise women of reproductive potential to notify health care professional if pregnancy is planned or suspected or if breastfeeding.
