- Techniques for minimizing discomfort during local anesthetic administration are often overlooked in modern clinical practice. Proper administration technique can reduce patient discomfort, improve patient satisfaction with service, and improve the procedure's outcome.
- The 2 main classes of injectable local anesthetics are amides and esters. Amides are more widely used and include lidocaine (Xylocaine) and bupivacaine (Marcaine). Esters, represented by procaine (Novocain), have a slower onset of action than amides and a higher rate of allergic reactions.
- Individuals with allergy to 1 class of anesthetics generally can receive another class safely.
- Many patients claim allergy to "caine" drugs, but they actually have experienced a vagal response or other systemic response to receiving an injection.
- If the exact nature of a prior reaction cannot be ascertained, administration of diphenhydramine hydrochloride (Benadryl) can provide sufficient anesthesia for small surgical procedures. 12 mL of diphenhydramine (25 mg/mL) solution is diluted with 14 mL of normal saline for intradermal (not subdermal) injection.
- Epinephrine in a local anesthetic solution prolongs the duration of the anesthetic and reduces bleeding by producing local vasoconstriction. Use of epinephrine also permits use of larger volumes of anesthetic. An average-sized adult (70 kg) can safely receive up to 28 mL (4 mg/kg) of 1% lidocaine and up to 49 mL (7 mg/kg) of 1% lidocaine with epinephrine.
- Historically, physicians have been taught to avoid administering solutions with epinephrine to body sites served by single arteriese.g., "fingers, toes, penis, and end of nose." The safety of administering epinephrine to the tip of the nose or to digits has been documented in some reports, but limiting use of epinephrine in these sites is prudent in the current medicolegal climate.
- Local anesthetics can be injected intradermally or subdermally.
- Intradermal administration produces a visible wheal in the skin, and the onset of action of the anesthetic is almost immediate.
- Intradermal injection of a large volume of solution can stretch pain sensors in the skin, aiding in anesthetic effect.
- Intradermal injection is especially useful for shave excisions, because anesthetic solution effectively thickens dermis, elevates the lesion, and prevents inadvertent penetration beneath dermis.
Recommendations to Reduce Discomfort of Local Anesthesia
- Stretch skin using nondominant hand during administration.
- Encourage the patient to talk as a distraction and for monitoring for vagal responses.
- Talk to the patient during administration; silence increases patient discomfort.
- Use the smallest gauge needle possible (preferably 30 gauge).
- Consider spraying aerosol refrigerant onto the skin before needle insertion.
- Consider vibrating nearby skin or patting distant sites to distract the patient during administration.
- Administer anesthetic at room temperature (i.e., nonchilled solutions).
- Insert the needle through enlarged pores, a scar, or hair follicles (i.e., less sensitive sites).
- Pause after the needle penetrates the skin to allow for patient recovery and relaxation.
- Inject a small amount of anesthetic and pause, allowing the anesthetic to take effect.
- Empower the patient by temporarily stopping the injection when burning is detected.
- Inject anesthetics slowly.
- Begin the injection subdermally and then withdraw the needle tip for intradermal injection.
- Consider addition of bicarbonate to buffer the acidity of the anesthetic.
- Permit adequate time for the anesthetic to take effect before initiating the surgical procedure.