Disorders and Drugs Associated with Altered Serum Phosphorus/Phosphate

[Show Table Outline]

Increased Levels (Hyperphosphatemia)

Disorders

• Diabetic ketoacidosis
• Renal failure
• Vitamin D intoxication
• Hypercalcemia
• Prolonged immobilization
• Hypoparathyroidism
• Pseudohypoparathyroidism
• Bone growth or active bone formation
• Hyperthyroidism
• Acromegaly
• Sarcoidosis
• Pyloric obstruction
• Milk-alkali syndrome

Drugs

• Sodium phosphate
• Heparin
• Phenytoin (Dilantin)
• Posterior pituitary injection (Pituitrin)
• Androgens

Decreased Levels (Hypophosphatemia)

Disorders

• Recovery phase of diabetic ketoacidosis
• Renal tubular acidosis
• Hypocalcemia
• Vitamin D deficiency
• Hyperparathyroidism
• Carbohydrate ingestion
• Malnutrition
• Malabsorption syndromes
• Hypothyroidism
• Hypopituitarism
• Alcoholism
• Prolonged vomiting and diarrhea

Drugs

• Acetazolamide (Diamox)
• Aluminum hydroxide
• Insulin
• Epinephrine

[Table Outline]

• Increased Levels (Hyperphosphatemia)
• Decreased Levels (Hypophosphatemia)