Causes of Altered Uric Acid Levels
- Excessive dietary purines
- Polycythemia
- Gout
- Psoriasis
- Type III hyperlipidemia
- Chemotherapy, radiation therapy for malignancies
- von Gierke's disease
- Sickle cell anemia
- Pernicious anemia
- Acute tissue destruction (infection, starvation, exercise)
- Eclampsia, hypertension
- Hyperparathyroidism
- Decreased excretion from lactic acidosis, ketoacidosis, renal failure, congestive heart failure
Drugs
- Alcohol
- Aspirin (<2 g/day)
- Thiazide diuretics
- Diazoxide (Hyperstat)
- Epinephrine
- Ethacrynic acid (Edecrin)
- Furosemide
- Phenothiazines
- Dextran
- Methyldopa
- Ascorbic acid
- Aminophylline
- Antibiotics (gentamicin)
- Griseofulvin
- Rifampin
- Triamterene (Dyrenium)
- Fanconi's syndrome
- Wilson's disease
- Yellow atrophy of the liver
Drugs
- Probenecid
- Sulfinpyrazone
- Aspirin (>4 g/day)
- Adrenocorticotropic hormone, corticosteroids
- Coumarin
- Estrogens
- Allopurinol
- Acetohexamide (Dymelor)
- Azathioprine (Imuran)
- Clofibrate
- 2-Phenylcinchoninic acid (Cinchophen)
- Chlorprothixene (Taractan)
- Mannitol
- Marijuana