Overview of Causes of Altered Platelet Function
| Increased Function | Decreased Function |
|---|---|
| Trauma | Severe liver disease |
| Surgery | Uremia |
| Fractures | Myeloproliferative disorders |
| Strenuous exercise | Dysproteinemias - Glanzmann's thrombasthenia |
| Pregnancy | Bernard-Soulier syndrome (hereditary giant platelet syndrome) - Idiopathic thrombocytopenic purpura - Infectious mononucleosis - von Willebrand's disease - Drugs such as aspirin and other anti-inflammatory agents, antihistamines, antidepressants, alcohol, methylxanthines |