Causes of Positive Rumple-Leeds Capillary Fragility Test
| Strongly positive (grade 4) | Aplastic anemia Chronic renal disease Glanzmann's thrombasthenia Idiopathic thrombocytopenic purpura (ITP) Leukemia Thrombocytopenia caused by acute infectious disease (measles, influenza, scarlet fever) |
| Moderately positive (grade 3) | Hepatic cirrhosis |
| Slightly positive (grade 2) | Allergic and senile purpuras Decreased estrogen levels Deficiency of vitamin K, factor VII, fibrinogen, or prothrombin Dysproteinemia Polycythemia vera von Willebrand's disease |