Irritant Contact Dermatitis (ICD)
Etiology: Acute or chronic/cumulative direct nonimmunologic inflammatory reaction to toxic injury, e.g., by chemical/irritant agents. Occurs in all individuals exposed to chemicals, given sufficient exposure times and concentrations; no previous exposure necessary.
History: Regular exposure to common irritants: water, soap, detergents, solvents, alcohol. Pain, burning, and stinging exceed pruritus early on. Those with history of atopic dermatitis are more susceptible.
Physical: Ill-defined erythematous, scaling, papulovesicular dermatitis; chronicscaling lichenified dermatitis.
Investigations: Patch testing to rule out ACD.
DDx: Dermatitisallergic contact atopic, nummular, seborrheic, stasis; cellulitis; drug reaction.
Prevention: Avoid irritant exposure by use of barriers (gloves, barrier creams) and/or by using less irritating materials as substitutes.
Treatment: Liberal use of nonsensitizing moisturizers (e.g., plain petroleum jelly) +/- topical steroids.