¹https://doi.org/10.1002/14651858.CD001869.pub9

¹Note on sinus-type headache: these are often migraine headaches misdiagnosed as sinus-type. Sinus-type headaches are defined by the International Classification of Headache Disorders (ICHD-II) as headache with purulent nasal discharge, pathologic sinus finding by imaging, and headache localized to specific facial and cranial areas of the sinuses.

¹CSF-specific oligoclonal bands can substitute for “dissemination in time” for the purposes of these criteria.

¹N Engl J Med. 2018 Jan 4;378(1):11-21. https://pubmed.ncbi.nlm.nih.gov/29129157/

²N Engl J Med. 2018;378:708-718. https://pubmed.ncbi.nlm.nih.gov/29364767/