Population: Adults with left ventricular thrombus.

Organization

AHA 2022

Recommendations

–Highest risk of LV thrombus 2 wk to 1 mo after STEMI.

–Consider low-dose anticoagulant (DOAC) for 1–3 mo if poor LV thrombus is due to MI.

–If “specified” dilated cardiomyopathy (due to Takotsubo, hypertrophic cardiomyopathy, peripartum cardiomyopathy, LV noncompaction, amyloidosis, Chagas disease, eosinophilic myocarditis) puts patient at high risk for LV thrombus, employ shared decision-making and consider indefinite anticoagulation.

–If subsequent echo shows resolution of thrombus (and/or a major bleed episode occurs), discontinue anticoagulation.

Source

–Circulation. 2022;146:e205-e223.