No clear biological function in humans has been identified. May serve as a cofactor of metalloenzymes and facilitate iron absorption or metabolism in microorganisms
| Life Stage Group | RDA/AI* | ULa (mg/d) |
|---|---|---|
| Infants | ||
| 0–6 mo | ND | ND |
| 7–12 mo | ND | ND |
| Children | ||
| 1–3 yr | ND | 0.2 |
| 4–8 yr | ND | 0.3 |
| Males | ||
| 9–13 yr | ND | 0.6 |
| 14–18 yr | ND | 1.0 |
| 19–30 yr | ND | 1.0 |
| 31–50 yr | ND | 1.0 |
| 50–70 yr | ND | 1.0 |
| >70 yr | ND | 1.0 |
| Females | ||
| 9–13 yr | ND | 0.6 |
| 14–18 yr | ND | 1.0 |
| 19–30 yr | ND | 1.0 |
| 31–50 yr | ND | 1.0 |
| 50–70 yr | ND | 1.0 |
| >70 yr | ND | 1.0 |
| Pregnancy | ||
| <=18 yr | ND | 1.0 |
| 19–30 yr | ND | 1.0 |
| 31–50 yr | ND | 1.0 |
| Lactation | ||
| <=18 yr | ND | 1.0 |
| 19–30 yr | ND | 1.0 |
| 31–50 yr | ND | 1.0 |
Nuts, legumes, cereals, sweeteners, chocolate milk powder, chocolate candy
Adverse Effects of Excessive Consumption
Decreased body weight gain
Note: As observed in animal studies
Individuals with preexisting nickel hypersensitivity (from previous dermal exposure) and kidney dysfunction are distinctly susceptible to the adverse effects of excess nickel intake.