Purine Analogs - Flowchart
Purine Analogs - Flowchart Purine Analogs Purine Analogs
«Flowchart»

ProDrug

fludarabine

ProDrug

fludarabine

ProDrug

ProDrug

fludarabine

Active Drug

F-ara-A

Active Drug

F-ara-A

Active Drug

Active Drug

F-ara-A

Deoxycytidine Kinase

F-ara-AMP

Deoxycytidine Kinase

F-ara-AMP

Deoxycytidine Kinase

Deoxycytidine Kinase

F-ara-AMP

F-ara-AdP

F-ara-AdP

F-ara-AdP

Active Drug

F-ara-A

Active Drug

Active Drug

F-ara-A

F-ara-A

F-ara-ATP

F-ara-ATP

F-ara-ATP

F-ara-AMP

F-ara-AMP

F-ara-AMP

End

End

End

dADP

dADP

dADP

RNA

RNA

RNA RNA

DNA

DNA

DNA DNA

ADP

RNR

ADP

ADP

RNR

RNR RNR

F-ara-ADP

F-ara-ADP

F-ara-ADP

dATP

dATP

dATP

DNA

DNA

DNA DNA

dADP

dADP

dADP