3.A 54-year-old man with history of pT3N1M0 colon adenocarcinoma is undergoing adjuvant chemotherapy with FOLFOX. The second day of chemo, he is admitted to the emergency department with severe chest pain. Echocardiographs before surgery (top) and in the emergency department (bottom) are shown. What it the most likely cause of this condition?

A. Oxaliplatin-induced sympathetic stimulation

B. 5-FU–induced coronary vasospasm

C. Hypersensitivity reaction to leucovorin

D. Rapid infusion of oxaliplatin