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Table 8-17

(see Antiulcer Agents)

Drug and DosageUseActionAssessment: Side Effects
Antiadrenal Agent
Aminoglutethimide (Cytadren)—PO 250 mg q6hCushing’s syndromeInhibits enzymatic conversion of cholesterol to pregnenolone, thus reducing synthesis of adrenal glucocorticoids/mineralocorticoidsCortical hypofunction, hypotension, hypothyroidism
NURSING IMPLICATIONS: Monitor: vital signs, laboratory values, disease signs and symptoms; observe frequently during periods of stress