46. A family member asks a nurse about possible treatments for Stage III Alzheimer's disease (AD). Which statement by the nurse is correct?
. High doses of vitamin E may slow disease progression.
. The benefits of NSAIDs have been proven.
. The risks of herbals, such as ginkgo biloba, are greater than any benefit.
. Recent research has shown hormone replacement improves cognition.
Test-Taking Tip
Look for an option that is different from the othersonly one option raises the potential risks of a drug. Drug therapy does not work consistently in all AD clients.
Content Area: Geriatrics, Neurological; Integrated Process: Teaching and Learning; Cognitive Level: Application; Client Need/Subneed: Physiological Integrity/Physiological Adaptation/Alterations in Body Systems
.
Answer 1 is incorrect because only drugs that are reversible inhibitors of cholinesterase have benefitted in slowing disease progression in mild to moderate Alzheimer's disease. Stage III is a late stage with severe dementia. Answer 2 is incorrect because only drugs that are reversible inhibitors of cholinesterase have benefitted mild to moderate Alzheimer's disease, not Stage III. Answer 3 is correct because families are often desperate to find a treatment, and there may be serious side effects. They need to discuss alternative therapies with the physician. Answer 4 is incorrect because only drugs that are reversible inhibitors of cholinesterase have benefitted cognition in mild to moderate Alzheimer's disease, not Stage III.