| Drug and Dosage | Use | Action | Assessment: Side Effects |
|---|---|---|---|
| Aminocaproic acid (Amicar)—PO, IV 5-gm loading dose; 1 gm/hr to 30 gm in 24 hr | Management of streptokinase or urokinase overdose | Inhibits plasminogen activator and antagonizes plasmin | Hypotension, bradycardia, cardiac arrhythmias |
| NURSING IMPLICATIONS: Give slowly IV to prevent side effects; not recommended for disseminated intravascular coagulation (DIC) | |||