30. A nurse is caring for a client who is experiencing serotonin syndrome. Which serotonergic drugs should a nurse recognize as possibly contributing to this problem?
Select all that apply.
Test-Taking Tip
Remember the medications that affect serotonin end in "ine."
Content Area: Mental Health, Pharmacology; Integrated Process: Nursing Process, Implementation; Cognitive Level: Application; Client Need/Subneed: Physiological Integrity/Pharmacological and Parenteral Therapies/Adverse Effects/Contraindications/Interactions
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Answer 1 is correct because duloxetine (Cymbalta) is a serotonin-norepinephrine reuptake inhibitor that can lead to serotonin syndrome (e.g., uncoordinated movements, diarrhea, or tremors). Answer 2 is correct because fluoxetine (Prozac) is a selective serotonin reuptake inhibitor that can lead to serotonin syndrome. Answer 3 is incorrect because aripiprazole (Abilify) is an antipsychotic and does not inhibit the reuptake of serotonin. Answer 4 is incorrect because haloperidol (Haldol) is an antipsychotic and does not inhibit the reuptake of serotonin. Answer 5 is correct because paroxetine (Paxil) is a selective serotonin reuptake inhibitor that can lead to serotonin syndrome.