| Drug and Dosage | Use | Action | Assessment: Side Effects |
|---|---|---|---|
| Baclofen (Lioresal)—PO 5 mg 3 times daily up to 10–20 mg 4 times/day maintenance dose | Relief of spasticity of multiple sclerosis, spinal cord injury | Centrally acting skeletal muscle relaxant; depresses polysynaptic afferent reflex activity at spinal cord level | Pruritis, tinnitus; nausea, vomiting; diarrhea or constipation; drowsiness |
| NURSING IMPLICATIONS: Administer with food if GI symptoms; monitor for safety when ambulating; do not discontinue abruptly | |||
| Dantrolene sodium (Dantrium)—PO 25 mg/day–25 mg 2–3 times daily to 100 mg 4 times daily max. | See Baclofen | See Baclofen | See Baclofen |
| NURSING IMPLICATIONS: See Baclofen | |||