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Table 8-11

  1. Alkylating agents
    1. Alkyl sulfonates
      1. Busulfan ( Myleran )
    2. Ethylenimines
      1. Thiotepa
    3. Nitrogen mustards
      1. Chlorambucil ( Leukeran )
      2. Cyclophosphamide ( Cytoxan )
      3. Ifosfamide ( Ifex )
      4. Mechlorethamine hydrochloride ( Mustargen, HN2, nitrogen mustard)
      5. Melphalan (Alkeran, L-PAM, L-phenylalanine mustard)
    4. Nitrosoureas
      1. Carmustine (BCNU, BiCNU )
      2. Lomustine (CCNU, CeeNu )
      3. Semustine (methyl-CCNU)
      4. Streptozocin ( Zanosar, streptozotocin)
    5. Triazenes
      1. Dacarbazine ( DTIC-Dome )
  2. Antibiotics
    1. Anthracyclines
      1. Daunorubicin (daunomycin, Cerubidine)
      2. Doxorubicin hydrochloride (Adriamycin)
      3. Idarubicin (Idamycin)
    2. Bleomycins
      1. Bleomycin sulfate (Blenoxane)
    3. Dactinomycin (actinomycin D, Cosmegen)
    4. Mitomycin (mitomycin C, Mutamycin)
    5. Plicamycin (Mithracin)
  3. Antimetabolites
    1. Folate antagonist
      1. Methotrexate ( Folex, Mexate )
    2. Purine analogues
      1. Cladribine (2-chlorodeoxyadenosine, Leustatin )
      2. Fludarabine ( Fludara )
      3. Mercaptopurine (6-MP, Purinethol )
      4. Pentostatin (deoxycoformycin, Nipent )
      5. Thioguanine (6-TG, 6-thioguanine)
    3. Pyrimidine analogues
      1. Cytarabine (cytosine arabinoside, Cytosar-U, ara-C)
      2. Fluorouracil (5-FU, 5-fluorouracil)
  4. Cellular growth factors
    1. Filgrastim ( Neupogen )
    2. Sargramostim ( Leukine, Prokine )
  5. Enzymes
    1. L-Asparaginase ( Elspar )
  6. Hormonal agents
    1. Androgens/antiandrogens
      1. Flutamide ( Eulexin )
    2. Estrogens/antiestrogens
      1. Estramustine phosphate sodium ( Emcyt )
      2. Tamoxifen citrate ( Nolvadex )
    3. Glucocorticoids
    4. Luteinizing hormone–releasing hormone (LH-RH) antagonists
      1. Buserelin ( Suprefact )
      2. Leuprolide ( Lupron )
    5. Octreotide acetate ( Sandostatin )
  7. Immunomodulating agents
    1. Interferons
      1. Interferon alfa-2a ( Roferon-A )
      2. Interferon alfa-2b ( Intron A )
    2. Interleukins: aldesleukin (interleukin-2, IL-2, Proleukin )
    3. Levamisole ( Ergamisol )
  8. Miscellaneous agents
    1. Carboplatin ( Paraplatin )
    2. Cisplatin (cis-platinum II, Platinol )
    3. Hexamethylmelamine (HMM)
    4. Hydroxyurea ( Hydrea )
    5. Mitotane (o,p´-DDD, Lysodren )
    6. Mitoxantrone ( Novantrone )
    7. Procarbazine ( N -methylhydrazine, Matulane, Natulan )
  9. Monoclonal antibodies
  10. Plant-derived products
    1. Epipodophyllotoxins
      1. Etoposide ( VePesid )
      2. Teniposide ( Vumon )
    2. Taxanes: paclitaxel ( Taxol )
    3. Vinca alkaloids
      1. Vinblastine ( Velban )
      2. Vincristine ( Oncovin )