Physiological Integrity

46. A nurse is to give 0.01 mcg/kg/min of nesiritide (Natrecor) to a client weighing 110 pounds. The premixed solution contains 1.5 mg of the drug in 250 mL of D₅W. The nurse correctly calculates that the client should receive _______ mL/hr of this medication.

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Question  Hint

Test-Taking Tip

Use dimensional analysis to solve for x.

Content Area: Adult Health, Pharmacology; Integrated Process: Nursing Process, Analysis; Cognitive Level: Analysis; Client Need/Subneed: Physiological Integrity/Pharmacological and Parenteral Therapies/Dosage Calculation

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Physiological Integrity

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Step 1: Convert the lb to kg: 110 lb × 1 kg/2.2 lb = 50 kg

Step 2: Calculate drug delivery rate for this client, who weighs 50 kg: 0.01 mcg/kg/min × 50 kg = 0.5 mcg/min

Step 3: Calculate volume delivery:
x mL/hr = 250 mL/1.5 mg × 1 mg/1000 mg × 0.5 mcg/min = 60 min/1 hr = 5 mL/hr

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