Approach to the Patient with Angioedema (Without Urticaria)
Approach to the Patient with Angioedema (Without Urticaria) - Flowchart Approach to the Patient with Angioedema (Without Urticaria) Approach to the Patient with Angioedema (Without Urticaria)
«Flowchart»

Start

Start

Start

Angioedema only

Angioedema only

Angioedema only

These may overlap

These may overlap

These may overlap

Drugs, ACE inhibitor

Drugs, ACE inhibitor

Drugs, ACE inhibitor

Family history

Family history

Family history

Idiopathic angioedema

Idiopathic angioedema

Idiopathic angioedema

Idiopathic angioedema

C4 level C1 inhibitor by protein and function

C4 level C1 inhibitor by protein and function

C4 level C1 inhibitor by protein and function

Abnormal

Abnormal

Abnormal Abnormal

Normal

Normal

Normal Normal

Hereditary angioedema


C1 INH protein + function abnormal = Type 1
C1 INH protein normal or elevated = Type 2

Hereditary angioedema


C1 INH protein + function abnormal = Type 1
C1 INH protein normal or elevated = Type 2

Hereditary angioedema

Hereditary angioedema


C1 INH protein + function abnormal = Type 1
C1 INH protein normal or elevated = Type 2


C1 INH protein + function abnormal = Type 1
C1 INH protein normal or elevated = Type 2

Normal C1Q level

Normal C1Q level

Normal C1Q level Normal C1Q level

Depressed C1Q level

Depressed C1Q level

Depressed C1Q level Depressed C1Q level

End

End

End

Search for lymphoma connective tissue disease Type 1

Search for lymphoma connective tissue disease Type 1

Search for lymphoma connective tissue disease Type 1

Anti C1 INH Type 2

Anti C1 INH Type 2

Anti C1 INH Type 2

Search for lymphoma connective tissue disease Type 1

Search for lymphoma connective tissue disease Type 1

Search for lymphoma connective tissue disease Type 1

Anti C1 INH Type 2

Anti C1 INH Type 2

Anti C1 INH Type 2