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Table 12-1

Classification of Commonly Used and New Nondepolarizing Neuromuscular Blockers According to Duration of Action (Time to T1 = 25% of Control) after Administration of 2 × ED95a

Duration of Action
LongIntermediateShort
(>50 min)(20-50 min)(10-20 min)
Steroidal compoundsPancuronium
  • Vecuronium

  • Rocuronium

Benzylisoquinolinium compoundsTubocurarine
  • Atracurium

  • Cisatracurium

Mivacurium

a The majority of nondepolarizing neuromuscular blockers are bisquaternary ammonium compounds. Tubocurarine, vecuronium, and rocuronium are monoquaternary compounds.